Overview of Adverse Transfusion Reaction Reporting for Hospitals in Canada - Supplement: Contacts for National ATR Report Recipients and Provincial TTISS Personnel

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Adverse Transfusion Reaction Subcommittee
Oksana Prokopchuk-Gauk, MD; Chair
Alan Tinmouth, MD
Lakshmi Rajappannair, MD
Lucinda Whitman, MD

Ad hoc members:
Mohammad Afzal (PHAC)
Maria Faraci, MD (Health Canada)
Gilles Lambert, MD (QHS/INSPQ)
Marianne Lavoie, MD (QHS/INSPQ)
Jessica Leung, PharmD (Health Canada)
Pierre-Aurèle Morin, MD (CCNMT)
Joanne Nixon (TTISS Ontario)
Andréanne Trottier (CCNMT, MSSS)
Jun Wu, MD, PhD (PHAC)
Matthew Yan, MD (CBS)
NAC Chair
Andrew Shih, MD
Provincial Ministry Representative
Katherine Logan (BC)
NAC Coordinator
Kendra Stuart
Date of Original Release
Publication Date
Health Canada – Canada Vigilance Program (as per Health Canada Blood Regulations & Food and Drug Regulations)

For reporting the investigation of Adverse Transfusion Reactions (ATRs) under the Blood Regulations, any form can be used but must include all the required information as specified in the Blood Regulations and Blood Regulations Guidance Document. Please refer to your provincial TTISS or blood coordinating office to determine which form is accepted and recommended.

For general blood-related inquiries or for suspected lot-associated issues (such as potential clusters of serious and non-serious reactions), you may wish to notify canada.vigilance.blood-sang@hc-sc.gc.ca prior to sending the reporting form(s).
*Please do not send copies of completed reports containing patient information to this email address.

As per the Protecting Canadians from Unsafe Drugs Act (Vanessa’s Law), which amended the Food and Drug Act, reporting is done directly to Health Canada – Canada Vigilance Program (CVP). To provide the greatest flexibility for hospitals, and to allow them to use their existing systems and processes, Health Canada is able to receive serious adverse drug reactions or medical device incident reports through a variety of submission methods such as fax, mail or the online reporting portal. Further details as to what products are subjected to these regulations can be found in the Overview document.

Hospitals must submit a report which includes all the required information as detailed in Health Canada – CVP’s Mandatory reporting of serious adverse drug reactions and medical device incidents by hospitals – Guidance document.

FAX or Mail appropriate form to:

Canada Vigilance Program
Health Products Surveillance and Epidemiology Bureau
Marketed Health Products Directorate
Health Products and Food Branch
Health Canada
Address Locator: 1908C
Ottawa ON K1A 0K9
Fax 1-866-678-6789
E-mail: canadavigilance@hc-sc.gc.ca (Do not send reports via email, for inquiries only)

We encourage hospitals to contact the Canada Vigilance Program (canadavigilance@hc-sc.gc.ca) should they have any questions related to the mandatory reporting regulations.

Hospitals are also strongly encouraged to send a copy of the completed report to the manufacturer. If you wish to send a copy of the report to the manufacturer, you may download the Manufacturer Contact List at the website: https://www.blood.ca/en/hospitals/plasma-products.


Canadian Blood Services or Héma-Québec

For ATRs that occur as a result of blood component transfusion where there is concern related to product quality and safety, reports must be submitted by hospitals to their local blood operator distribution site (Canadian Blood Services (CBS) or Héma-Québec (HQ)). CBS and HQ report to the Health Canada – CVP.

Should the hospital transfusion medicine lab manipulate the blood components implicated in the ATR (e.g. pooling the blood component which causes a bacterial infection), the hospital reports directly to Health Canada – CVP. There may be some discussion about the ATR with CBS or HQ to review the cause of the bacterial infection and determine whose responsibility it is to report (CBS or HQ, or the hospital transfusion medicine laboratory).

Within Québec, HQ also requires they receive all blood product ATR reports from hospitals, in addition to the Health Canada – CVP. A report on implicated products must also be completed by transfusion safety staff for submission to the Québec Hemovigilance System REIAT (Rapport d’événement indésirable associé à la transfusion) database.

Transfusion Transmitted Injuries Surveillance System (TTISS)

All ATRs are to be reported to the provincial/territorial TTISS Office, or the Institut national de santé publique du Québec (INSPQ) via the REIAT database in Québec. Some Canadian provinces may have an online database or provincial version of the ATR data submission form. Official paper versions of data collection documents for TTISS are:

  • Provinces/Territories (except Québec): Canadian Transfusion Adverse Event Reporting Form (CTAERF)
  • Québec: REIAT – Rapport d’événement indésirable associé à la transfusion.

Provinces and territories report aggregate de-identified data to the Public Health Agency of Canada as part of the National TTISS program. Each province/territory collects ATR data through various processes. Provincial/territorial contacts responsible for TTISS ATR data reporting are as follows:

  1. British Columbia & Yukon
    Aimee Beauchamp
    Lead, Business Operations, BC Provincial Blood Coordinating Office
    BC Provincial Laboratory Medicine Services
    Provincial Health Services Authority
    Office: 1867 West Broadway, 3rd Floor, Vancouver, BC V6J 4W1
    Office Phone: 604-714-2871 (working remotely, please use email for contact)
    abeauchamp@pbco.ca | www.pbco.ca
  2. Alberta
    Samantha Cassie
    Manager, Transfusion Medicine Services
    Divisional Services Branch, Pharmaceutical & Supplementary Benefits Division
    780-983-9811 (mobile)
    780-644-8969 (office)

    Henry Sintim
    Provincial TTISS Coordinator
  3. Saskatchewan
    Elaine Blais
    Manager, Transfusion Safety and Patient Blood Management, Clinical Excellence
    Saskatchewan Health Authority
    Cell: 306-441-7210
  4. Manitoba
    Shana Chiborak
    Nurse Manager, Blood Management Service
    Shared Health Manitoba

    Brittani Rainkie
    Nurse Coordinator, Blood Management Service
    Shared Health Manitoba
  5. Ontario
    Melanie St. John
    Provincial Coordinator
    McMaster Centre for Transfusion Research
    Website: https:\\ttiss.mcmaster.ca
  6. Québec
    Andréanne Trottier
    Conseillère en biovigilance
    Ministère de la Santé et de Services sociaux
    1075, chemin Sainte-Foy, 9e étage, Québec (Québec) G1S 2M1
    Téléphone : 581-814-9100, poste 62553
    Website: https://www.msss.gouv.qc.ca/professionnels/soins-et-services/biovigilance/fonctionnement/
  7. Nova Scotia
    Jennifer LeFrense
    Manager, Provincial Blood Coordinating Team
    Website: http://www.cdha.nshealth.ca/nova-scotia-provincial-blood-coordinating-team

    Michael Farrell
    Utilization Management Coordinator
    Nova Scotia Provincial Blood Coordinating Team
  8. New Brunswick
    Sophie Traer MacKinnon
    Health Care Consultant - NB Blood System Coordinator
    Conseillère en soins de santé - Coordinatrice du Système Sanguin du N.-B.
    Health Services Division/Division des services de santé
    Department of Health/Ministère de la Santé
    HSBC Place, 520 King Street
    Fredericton, New Brunswick E3B 6G3
  9. Newfoundland and Labrador
    Newfoundland and Labrador Provincial Blood Coordinating Program
  10. Prince Edward Island
    Ami MacQuarrie
    Medical Laboratory Specialist
    Queen Elizabeth Hospital
    PO Box 6600
    60 Riverside Dr.
    Charlottetown, PE C1A0E3
    Ph: 902 894 2329
    Email : anmacquarrie@ihis.org
  11. Northwest Territories
    Amy Richardson | Technical Specialist Transfusion Medicine
    Northwest Territories Health and Social Services Authority - Stanton Territorial Hospital |
    L'Administration des Services de Santé et des Services Sociaux des Territoires du Nord-Ouest- Hôpital territorial Stanton
    548 Byrne Road, PO Box 10/548, chemin Byrne, C. P. 10
    Yellowknife NT X1A 2N1
    Phone | Tél. : 867-767-9300 ext 46465
    Fax | Téléc. : 867-669-4306
    Email | Courriel : Amy_Richardson@gov.nt.ca