NAC Statement on Factor XIII Concentrate Use
Credits
Author
Ryan Lett, MD
Authors of Previous Version
Susan Nahirniak, MD
Alan Tinmouth, MD
Dana Devine, MD
Alan Tinmouth, MD
Dana Devine, MD
NAC Chair
Andrew Shih, MD
Provincial Ministry Representatives
Antje Helmuth (BC)
Pouya Pour (BC)
Pouya Pour (BC)
NAC Coordinator
Kendra Stuart
Date of Original Release
Publication Date
Recommendation
A librarian assisted literature review from 2013-2023 was performed reviewing the use of Factor XIII in clinical practice. There was no high-quality evidence found to support routine replacement without knowledge of existing Factor XIII levels. There is a need to assess outcomes based on testing in Canada.
Acknowledgments
The National Advisory Committee on Blood and Blood Products would like to acknowledge and thank the Saskatchewan Health Authority Library and Librarian Mark Mueller for providing the literature search required to update this recommendation.
The evidence search report performed by the Saskatchewan Health Authority Library which informed this recommendation can be found on pages 3 to 22 here.